Version 5.4
Homo sapiens Gene: TCF15
Summary
InnateDB Gene IDBG-38257.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TCF15
Gene Name transcription factor 15 (basic helix-loop-helix)
Synonyms bHLHa40; EC2; PARAXIS
Species Homo sapiens
Ensembl Gene ENSG00000125878
Encoded Proteins
IDBP-38259
transcription factor 15 (basic helix-loop-helix)
IDBP-806716
transcription factor 15 (basic helix-loop-helix)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is found in the nucleus and may be involved in the early transcriptional regulation of patterning of the mesoderm. The encoded basic helix-loop-helix protein requires dimerization with another basic helix-loop-helix protein for efficient DNA binding. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:603797-610398
Strand Reverse strand
Band p13
Transcripts
ENST00000246080 ENSP00000246080
ENST00000621005 ENSP00000483116
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0001756 somitogenesis
GO:0003016 respiratory system process
GO:0006351 transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0007498 mesoderm development
GO:0007517 muscle organ development
GO:0009952 anterior/posterior pattern specification
GO:0016265 death
GO:0036342 post-anal tail morphogenesis
GO:0042755 eating behavior
GO:0043583 ear development
GO:0043588 skin development
GO:0045198 establishment of epithelial cell apical/basal polarity
GO:0048339 paraxial mesoderm development
GO:0048644 muscle organ morphogenesis
GO:0048705 skeletal system morphogenesis
GO:0050884 neuromuscular process controlling posture
GO:0060231 mesenchymal to epithelial transition
GO:1901311 regulation of gene expression involved in extracellular matrix organization
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000068079
View Gene Order
ENSBTAG00000005750
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 6939
UniGene
RefSeq NM_004609
HUGO HGNC:11627
OMIM 601010
CCDS CCDS33432
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 6939

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca