Version 5.4
Homo sapiens Gene: SLC7A6
Summary
InnateDB Gene IDBG-38270.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC7A6
Gene Name solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
Synonyms LAT-2; LAT3; y+LAT-2
Species Homo sapiens
Ensembl Gene ENSG00000103064
Encoded Proteins
IDBP-38272
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
IDBP-38274
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
IDBP-750250
IDBP-751864
IDBP-748084
IDBP-744855
IDBP-746182
IDBP-749515
IDBP-750578
IDBP-749384
IDBP-752919
IDBP-747447
IDBP-811724
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:68264516-68301823
Strand Forward strand
Band q22.1
Transcripts
ENST00000219343 ENSP00000219343
ENST00000379152 ENSP00000368448
ENST00000563146 ENSP00000455487
ENST00000568024 ENSP00000457550
ENST00000566454 ENSP00000455064
ENST00000562863
ENST00000567325
ENST00000566579 ENSP00000456474
ENST00000568088 ENSP00000455357
ENST00000562727 ENSP00000456896
ENST00000563208
ENST00000566834 ENSP00000457758
ENST00000564708 ENSP00000456629
ENST00000563080 ENSP00000454824
ENST00000567346 ENSP00000463394
ENST00000618043 ENSP00000484012
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0015171 amino acid transmembrane transporter activity
GO:0015297 antiporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006461 protein complex assembly
GO:0006520 cellular amino acid metabolic process
GO:0006810 transport
GO:0006811 ion transport
GO:0006865 amino acid transport
GO:0007596 blood coagulation
GO:0050900 leukocyte migration
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031904
View Gene Order
ENSBTAG00000012112
Not yet available
Pathways
NETPATH
REACTOME
REACT_12560
Basigin interactions pathway
REACT_12051
Cell surface interactions at the vascular wall pathway
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_604
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.679580 Hs.724036 Hs.739359
RefSeq NM_001076785 NM_003983
HUGO
OMIM
CCDS CCDS32470
HPRD 12031
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca