Version 5.4
Homo sapiens Gene: GLYCTK
Summary
InnateDB Gene IDBG-38597.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLYCTK
Gene Name glycerate kinase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168237
Encoded Proteins
IDBP-38603
glycerate kinase
IDBP-379148
glycerate kinase
IDBP-476463
glycerate kinase
IDBP-475264
glycerate kinase
IDBP-477676
glycerate kinase
IDBP-484126
glycerate kinase
IDBP-477066
glycerate kinase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:52287089-52293476
Strand Forward strand
Band p21.2
Transcripts
ENST00000305690 ENSP00000301965
ENST00000436784 ENSP00000389175
ENST00000461183 ENSP00000417264
ENST00000486393 ENSP00000419868
ENST00000473032 ENSP00000418951
ENST00000471180 ENSP00000417526
ENST00000473583
ENST00000477382 ENSP00000419008
ENST00000489173
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008887 glycerate kinase activity
Biological Process
GO:0006468 protein phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020258
View Gene Order
ENSBTAG00000021695
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00260
Glycine, serine and threonine metabolism pathway
hsa00630
Glyoxylate and dicarboxylate metabolism pathway
hsa00561
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001144951 NM_145262 XM_005264878 XM_006712978
HUGO
OMIM
CCDS CCDS2852 CCDS46841
HPRD 13586
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca