Homo sapiens Gene: PPIC
Summary
InnateDB Gene IDBG-39025.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPIC
Gene Name peptidylprolyl isomerase C (cyclophilin C)
Synonyms CYPC;
Species Homo sapiens
Ensembl Gene ENSG00000168938
Encoded Proteins
peptidylprolyl isomerase C (cyclophilin C)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:123023250-123036741
Strand Reverse strand
Band q23.2
Transcripts
ENST00000306442 ENSP00000303057
ENST00000415659
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding
GO:0016018 cyclosporin A binding
GO:0051082 unfolded protein binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
GO:0006457 protein folding
GO:0007165 signal transduction
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.110364
RefSeq NM_000943
HUGO
OMIM
CCDS CCDS4133
HPRD 00459
IMGT
EMBL
GenPept
RNA Seq Atlas