Version 5.4
Homo sapiens Gene: SARNP
Summary
InnateDB Gene IDBG-39101.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SARNP
Gene Name SAP domain containing ribonucleoprotein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000205323
Encoded Proteins
IDBP-39103
SAP domain containing ribonucleoprotein
IDBP-596110
SAP domain containing ribonucleoprotein
IDBP-589807
SAP domain containing ribonucleoprotein
IDBP-592233
SAP domain containing ribonucleoprotein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that is upregulated in response to various cytokines. The encoded protein may play a role in cell cycle progression. A translocation between this gene and the myeloid/lymphoid leukemia gene, resulting in expression of a chimeric protein, has been associated with acute myelomonocytic leukemia. Pseudogenes exist on chromosomes 7 and 8. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:55752463-55817756
Strand Reverse strand
Band q13.2
Transcripts
ENST00000336133 ENSP00000337632
ENST00000546604 ENSP00000449409
ENST00000552884 ENSP00000448455
ENST00000552946
ENST00000552080 ENSP00000447690
ENST00000552207
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
Experimentally validated
Total 44 [view]
Protein-Protein 43 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006406 mRNA export from nucleus
GO:0006417 regulation of translation
Cellular Component
GO:0000346 transcription export complex
GO:0005634 nucleus
GO:0016607 nuclear speck
GO:0043231 intracellular membrane-bounded organelle
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_033082
HUGO
OMIM
CCDS CCDS8892
HPRD 16716
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca