Homo sapiens Gene: IGKV3-20
Summary
InnateDB Gene IDBG-403640.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IGKV3-20
Gene Name immunoglobulin kappa variable 3-20
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000239951
Encoded Proteins
immunoglobulin kappa variable 3-20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type IG_V_gene
Genomic Location Chromosome 2:89142574-89143160
Strand Reverse strand
Band p11.2
Transcripts
ENST00000492167 ENSP00000418649
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003823 antigen binding
GO:0005515 protein binding
GO:0034987 immunoglobulin receptor binding
Biological Process
GO:0003094 glomerular filtration
GO:0006955 immune response
GO:0006956 complement activation
GO:0006958 complement activation, classical pathway
GO:0019731 antibacterial humoral response
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 innate immune response
GO:0050776 regulation of immune response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0071748 monomeric IgA immunoglobulin complex
GO:0071751 secretory IgA immunoglobulin complex
GO:0071756 pentameric IgM immunoglobulin complex
GO:0072562 blood microparticle
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Regulation of actin dynamics for phagocytic cup formation pathway
Role of phospholipids in phagocytosis pathway
FCGR activation pathway
Classical antibody-mediated complement activation pathway
Initial triggering of complement pathway
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
Scavenging of heme from plasma pathway
FCERI mediated NF-kB activation pathway
Role of LAT2/NTAL/LAB on calcium mobilization pathway
Innate Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
Creation of C4 and C2 activators pathway
Adaptive Immune System pathway
Immune System pathway
Fcgamma receptor (FCGR) dependent phagocytosis pathway
Complement cascade pathway
FCERI mediated Ca+2 mobilization pathway
Signaling by the B Cell Receptor (BCR) pathway
FCERI mediated MAPK activation pathway
KEGG
INOH
B cell receptor signaling pathway
PID NCI
Cross-References
SwissProt P18136
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.704238
RefSeq
HUGO HGNC:5817
OMIM
CCDS
HPRD
IMGT IGKV3-20
EMBL AC096767
GenPept
RNA Seq Atlas