Homo sapiens Gene: PVT1
Summary
InnateDB Gene IDBG-405924.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PVT1
Gene Name Pvt1 oncogene (non-protein coding)
Synonyms LINC00079; NCRNA00079;
Species Homo sapiens
Ensembl Gene ENSG00000249859
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Gene Information
Type lincRNA
Genomic Location Chromosome 8:127794533-128101253
Strand Forward strand
Band q24.21
Transcripts
ENST00000504719
ENST00000524165
ENST00000523328
ENST00000521951
ENST00000517525
ENST00000523427
ENST00000517790
ENST00000522963
ENST00000518528
ENST00000523068
ENST00000521122
ENST00000513868
ENST00000520913
ENST00000519481
ENST00000517838
ENST00000512617
ENST00000521600
ENST00000522875
ENST00000523190
ENST00000522414
ENST00000617087
ENST00000612011
ENST00000615442
ENST00000616386
ENST00000613916
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.729316
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas