Version 5.4
| Homo sapiens Gene: CCL13 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-40707.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | CCL13 | ||||||||||||||||||
| Gene Name | chemokine (C-C motif) ligand 13 | ||||||||||||||||||
| Synonyms | CKb10; MCP-4; NCC-1; NCC1; SCYA13; SCYL1 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000181374 | ||||||||||||||||||
| Encoded Proteins |
chemokine (C-C motif) ligand 13
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Jul 2008] This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes during inflammation. It may also be involved in the recruitment of monocytes into the arterial wall during artherosclerosis. [provided by RefSeq, Sep 2014] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 17:34356452-34358610 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | q12 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME | |||||||||||||||||||
| KEGG |
Cytokine-cytokine receptor interaction pathway
Chemokine signaling pathway pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | Q99616 | ||||||||||||||||||
| TrEMBL | O95690 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 6357 | ||||||||||||||||||
| UniGene | Hs.414629 | ||||||||||||||||||
| RefSeq | NM_005408 | ||||||||||||||||||
| HUGO | HGNC:10611 | ||||||||||||||||||
| OMIM | 601391 | ||||||||||||||||||
| CCDS | CCDS11281 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AC002482 AJ001634 BC008621 BT007385 CH471147 CR450337 U46767 U59808 X98306 Z77650 Z77651 | ||||||||||||||||||
| GenPept | AAB38703 AAB67307 AAD09362 AAH08621 AAP36049 CAA04888 CAA66950 CAB01111 CAB01112 CAG29333 EAW80205 EAW80206 | ||||||||||||||||||
| RNA Seq Atlas | 6357 | ||||||||||||||||||