Homo sapiens Gene: PRB1
Summary
InnateDB Gene IDBG-408393.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRB1
Gene Name proline-rich protein BstNI subfamily 1
Synonyms PM; PMF; PMS; PRB1L; PRB1M;
Species Homo sapiens
Ensembl Gene ENSG00000251655
Encoded Proteins
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a precursor for proline-rich salivary proteins. This and five other genes that encode salivary proline-rich proteins (PRPs)form a PRP gene cluster in the chromosomal 12p13 region. Precursor salivary PRPs are cleaved multiple times to produce a diversity of secreted peptides. Alleles of this gene exhibit tandem repeat length variation in the coding region as well as polymorphic cleavage sites and polymorphic stop codons. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:11351823-11395566
Strand Reverse strand
Band p13.2
Transcripts
ENST00000240636
ENST00000500254 ENSP00000420826
ENST00000545626 ENSP00000444249
ENST00000546254 ENSP00000442127
ENST00000612352 ENSP00000483046
ENST00000613702 ENSP00000477917
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
Salivary secretion pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 5542
UniGene
RefSeq NM_005039 NM_199353 NM_199354
HUGO HGNC:9337
OMIM 180989
CCDS CCDS55805 CCDS8642
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 5542