Version 5.4
Homo sapiens Gene: ZNF208
Summary
InnateDB Gene IDBG-41056.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF208
Gene Name zinc finger protein 208
Synonyms PMIDP; ZNF95
Species Homo sapiens
Ensembl Gene ENSG00000160321
Encoded Proteins
IDBP-236069
zinc finger protein 208
IDBP-765111
IDBP-764845
IDBP-762971
IDBP-765462
IDBP-765249
IDBP-807243
zinc finger protein 208
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Zinc finger proteins (ZNFs), such as ZNF208, bind DNA and, through this binding, regulate gene transcription. Most ZNFs contain conserved C2H2 motifs and are classified as Kruppel-type zinc fingers. A conserved protein motif, termed the Kruppel-associated box (KRAB) domain, mediates protein-protein interactions (Eichler et al., 1998 [PubMed 9724325]). See ZNF91 (MIM 603971) for further information on ZNFs.[supplied by OMIM, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:21932958-22010949
Strand Reverse strand
Band p12
Transcripts
ENST00000397126 ENSP00000380315
ENST00000601773 ENSP00000469887
ENST00000599916 ENSP00000469254
ENST00000597040 ENSP00000472406
ENST00000599723 ENSP00000473026
ENST00000601993 ENSP00000471831
ENST00000609966 ENSP00000476345
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt O43345
TrEMBL M0QXL7 M0QYK4 M0R1F2 M0R293
UniProt Splice Variant
Entrez Gene 7757
UniGene Hs.541334 Hs.732975
RefSeq NM_007153
HUGO HGNC:12999
OMIM 603977
CCDS CCDS54240
HPRD
IMGT
EMBL AC003973
GenPept AAB94784
RNA Seq Atlas 7757

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca