Version 5.4
Homo sapiens Gene: SLITRK5
Summary
InnateDB Gene IDBG-41584.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLITRK5
Gene Name SLIT and NTRK-like family, member 5
Synonyms bA364G4.2; LRRC11
Species Homo sapiens
Ensembl Gene ENSG00000165300
Encoded Proteins
IDBP-41586
SLIT and NTRK-like family, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:87672615-87696272
Strand Forward strand
Band q31.2
Transcripts
ENST00000325089 ENSP00000366283
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007268 synaptic transmission
GO:0007409 axonogenesis
GO:0007625 grooming behavior
GO:0009410 response to xenobiotic stimulus
GO:0021756 striatum development
GO:0030534 adult behavior
GO:0043588 skin development
GO:0048813 dendrite morphogenesis
GO:0072358 cardiovascular system development
Cellular Component
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033214
View Gene Order
ENSBTAG00000010129
Not yet available
Cross-References
SwissProt O94991
TrEMBL
UniProt Splice Variant
Entrez Gene 26050
UniGene Hs.591208 Hs.604914
RefSeq NM_015567 XM_005254038 XM_005254039
HUGO HGNC:20295
OMIM 609680
CCDS CCDS9465
HPRD
IMGT
EMBL AB020725 AK024251 AL603883 BC098106 BC103509 CH471085
GenPept AAH98106 AAI03510 BAA74941 BAG51280 CAH73026 EAX08917
RNA Seq Atlas 26050

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca