Homo sapiens Gene: CDH20
Summary
InnateDB Gene IDBG-4206.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDH20
Gene Name cadherin 20, type 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101542
Encoded Proteins
cadherin 20, type 2
cadherin 20, type 2
cadherin 20, type 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:61333582-61555773
Strand Forward strand
Band q21.33
Transcripts
ENST00000262717 ENSP00000262717
ENST00000536675 ENSP00000444767
ENST00000538374 ENSP00000442226
ENST00000587582
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9HBT6
TrEMBL K7ESP2 Q8N9J3
UniProt Splice Variant
Entrez Gene 28316
UniGene Hs.671510
RefSeq NM_031891 XM_005266682 XM_005266684
HUGO HGNC:1760
OMIM 605807
CCDS CCDS11977
HPRD 10429
IMGT
EMBL AC006203 AC025656 AC090409 AF217289 AK094366 BC101047 BC101048 BC101049 CH471096
GenPept AAG23739 AAI01048 AAI01049 AAI01050 BAC04340 EAW63108
RNA Seq Atlas 28316