Homo sapiens Gene: ADAMTS18 | |||||||||
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Summary | |||||||||
InnateDB Gene | IDBG-42966.6 | ||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
Gene Symbol | ADAMTS18 | ||||||||
Gene Name | ADAM metallopeptidase with thrombospondin type 1 motif, 18 | ||||||||
Synonyms | |||||||||
Species | Homo sapiens | ||||||||
Ensembl Gene | ENSG00000140873 | ||||||||
Encoded Proteins |
ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
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Protein Structure | |||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||
Entrez Gene | |||||||||
Summary |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||
Type | Protein coding | ||||||||
Genomic Location | Chromosome 16:77247813-77435114 | ||||||||
Strand | Reverse strand | ||||||||
Band | q23.1 | ||||||||
Transcripts | |||||||||
Interactions | |||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||
NETPATH | |||||||||
REACTOME |
Post-translational protein modification pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
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KEGG | |||||||||
INOH | |||||||||
PID NCI | |||||||||
Cross-References | |||||||||
SwissProt | |||||||||
TrEMBL | |||||||||
UniProt Splice Variant | |||||||||
Entrez Gene | |||||||||
UniGene | Hs.188746 Hs.607303 | ||||||||
RefSeq | NM_199355 XM_006721156 XM_006721157 XM_006721158 | ||||||||
HUGO | |||||||||
OMIM | |||||||||
CCDS | CCDS10926 | ||||||||
HPRD | 06333 | ||||||||
IMGT | |||||||||
EMBL | |||||||||
GenPept | |||||||||
RNA Seq Atlas | |||||||||