Version 5.4
Homo sapiens Gene: HSD17B2
Summary
InnateDB Gene IDBG-43855.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSD17B2
Gene Name hydroxysteroid (17-beta) dehydrogenase 2
Synonyms EDH17B2; HSD17; SDR9C2
Species Homo sapiens
Ensembl Gene ENSG00000086696
Encoded Proteins
IDBP-43857
hydroxysteroid (17-beta) dehydrogenase 2
IDBP-754058
IDBP-748409
IDBP-745640
IDBP-747511
IDBP-750425
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:82035004-82098534
Strand Forward strand
Band q23.3
Transcripts
ENST00000199936 ENSP00000199936
ENST00000569351 ENSP00000454931
ENST00000568090 ENSP00000456529
ENST00000563491 ENSP00000455992
ENST00000566213 ENSP00000457943
ENST00000566838 ENSP00000456471
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 0
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
GO:0047035 testosterone dehydrogenase (NAD+) activity
Biological Process
GO:0001701 in utero embryonic development
GO:0001890 placenta development
GO:0006694 steroid biosynthetic process
GO:0008152 metabolic process
GO:0032526 response to retinoic acid
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031844
View Gene Order
ENSBTAG00000003234
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00140
Steroid hormone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL H3BNN1 H3BQY3
UniProt Splice Variant
Entrez Gene 3294
UniGene Hs.629161
RefSeq NM_002153
HUGO HGNC:5211
OMIM 109685
CCDS CCDS10936
HPRD 00186
IMGT
EMBL AC092142
GenPept
RNA Seq Atlas 3294

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca