Homo sapiens Gene: HSD17B2
Summary
InnateDB Gene IDBG-43855.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSD17B2
Gene Name hydroxysteroid (17-beta) dehydrogenase 2
Synonyms EDH17B2; HSD17; SDR9C2;
Species Homo sapiens
Ensembl Gene ENSG00000086696
Encoded Proteins
hydroxysteroid (17-beta) dehydrogenase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:82035004-82098534
Strand Forward strand
Band q23.3
Transcripts
ENST00000199936 ENSP00000199936
ENST00000569351 ENSP00000454931
ENST00000568090 ENSP00000456529
ENST00000563491 ENSP00000455992
ENST00000566213 ENSP00000457943
ENST00000566838 ENSP00000456471
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 0
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity
GO:0047035 testosterone dehydrogenase (NAD+) activity
Biological Process
GO:0001701 in utero embryonic development
GO:0001890 placenta development
GO:0006694 steroid biosynthetic process
GO:0008152 metabolic process
GO:0032526 response to retinoic acid
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Steroid hormone biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.629161
RefSeq NM_002153
HUGO
OMIM
CCDS CCDS10936
HPRD 00186
IMGT
EMBL
GenPept
RNA Seq Atlas