Homo sapiens Gene: PCED1A
Summary
InnateDB Gene IDBG-43963.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCED1A
Gene Name PC-esterase domain containing 1A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000132635
Encoded Proteins
family with sequence similarity 113, member A
family with sequence similarity 113, member A
family with sequence similarity 113, member A
family with sequence similarity 113, member A
PC-esterase domain containing 1A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the GDSL/SGNH superfamily. Members of this family are hydrolytic enzymes with esterase and lipase activity and broad substrate specificity. This protein belongs to the Pmr5-Cas1p-esterase subfamily in that it contains the catalytic triad comprised of serine, aspartate and histidine and lacks two conserved regions (glycine after strand S2 and GxND motif). A pseudogene of this gene has been identified on the long arm of chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Sep 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:2835314-2841190
Strand Reverse strand
Band p13
Transcripts
ENST00000356872 ENSP00000349334
ENST00000360652 ENSP00000353868
ENST00000439542 ENSP00000401711
ENST00000448755 ENSP00000388935
ENST00000474714 ENSP00000474824
ENST00000487501
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9H1Q7
TrEMBL X6RFT7
UniProt Splice Variant
Entrez Gene 64773
UniGene
RefSeq NM_022760 XM_005260804 NM_001271168 XM_005260805
HUGO HGNC:16212
OMIM
CCDS CCDS13035 CCDS59442
HPRD 12786
IMGT
EMBL AK026029 AK056353 AL161656 AY211913 BC008864 BC014247 BC037240 BC051816
GenPept AAH08864 AAH14247 AAH37240 AAH51816 AAO65166 BAB15328 BAB71160 CAC21463 CAC21464 CAI12118 CAI12119
RNA Seq Atlas 64773