Version 5.4
Homo sapiens Gene: FFAR3
Summary
InnateDB Gene IDBG-44188.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FFAR3
Gene Name free fatty acid receptor 3
Synonyms FFA3R; GPR41
Species Homo sapiens
Ensembl Gene ENSG00000185897
Encoded Proteins
IDBP-44190
free fatty acid receptor 3
IDBP-761412
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:35358460-35360485
Strand Forward strand
Band q13.12
Transcripts
ENST00000327809 ENSP00000328230
ENST00000594310 ENSP00000469522
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0008289 lipid binding
Biological Process
GO:0002385 mucosal immune response
GO:0002720 positive regulation of cytokine production involved in immune response
GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0014061 regulation of norepinephrine secretion
GO:0032722 positive regulation of chemokine production
GO:0045776 negative regulation of blood pressure
GO:0046885 regulation of hormone biosynthetic process
GO:0071398 cellular response to fatty acid
GO:0090276 regulation of peptide hormone secretion
GO:2001275 positive regulation of glucose import in response to insulin stimulus
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019429
View Gene Order
ENSBTAG00000013791
Not yet available
Pathways
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_21268
Free fatty acid receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.248055
RefSeq NM_005304
HUGO
OMIM
CCDS CCDS12459
HPRD 04823
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca