Version 5.4
Homo sapiens Gene: TMEM5
Summary
InnateDB Gene IDBG-44701.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM5
Gene Name transmembrane protein 5
Synonyms HP10481; MDDGA10
Species Homo sapiens
Ensembl Gene ENSG00000118600
Encoded Proteins
IDBP-44703
transmembrane protein 5
IDBP-589505
transmembrane protein 5
IDBP-594958
transmembrane protein 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a type II transmembrane protein that is thought to have glycosyltransferase function. Mutations in this gene result in cobblestone lissencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:63779803-63809558
Strand Forward strand
Band q14.2
Transcripts
ENST00000261234 ENSP00000261234
ENST00000433461
ENST00000536219
ENST00000543342 ENSP00000440845
ENST00000537982
ENST00000537373 ENSP00000440280
ENST00000535963
ENST00000623171
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 1 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034620
View Gene Order
ENSBTAG00000004753
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.216386 Hs.716859
RefSeq NM_001278237 NM_014254 XM_005268562 XM_006719195
HUGO
OMIM
CCDS CCDS61179 CCDS8966
HPRD 12057
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca