Version 5.4
Homo sapiens Gene: SELM
Summary
InnateDB Gene IDBG-4473.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SELM
Gene Name selenoprotein M precursor
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198832
Encoded Proteins
IDBP-228591
Selenoprotein M
IDBP-294411
Selenoprotein M
IDBP-808045
selenoprotein M precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This gene is expressed in a variety of tissues, and the protein is localized to the perinuclear structures. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:31104772-31120069
Strand Reverse strand
Band q12.2
Transcripts
ENST00000400299 ENSP00000383155
ENST00000402395 ENSP00000384564
ENST00000490967
ENST00000465536
ENST00000491958
ENST00000495533
ENST00000460642
ENST00000469262
ENST00000465447
ENST00000611680 ENSP00000480176
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0010269 response to selenium ion
GO:0035264 multicellular organism growth
GO:0035934 corticosterone secretion
GO:0042445 hormone metabolic process
GO:0060612 adipose tissue development
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000075702
View Gene Order
ENSBTAG00000031279
Not yet available
Cross-References
SwissProt
TrEMBL A0A024R1H1
UniProt Splice Variant
Entrez Gene 140606
UniGene
RefSeq NM_080430
HUGO
OMIM 610918
CCDS CCDS43003
HPRD
IMGT
EMBL CH471095
GenPept EAW59934 EAW59935
RNA Seq Atlas 102725415 140606

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca