Version 5.4
Homo sapiens Gene: TRPV6
Summary
InnateDB Gene IDBG-45160.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRPV6
Gene Name transient receptor potential cation channel, subfamily V, member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165125
Encoded Proteins
IDBP-45162
transient receptor potential cation channel, subfamily V, member 6
IDBP-386974
transient receptor potential cation channel, subfamily V, member 6
IDBP-386975
transient receptor potential cation channel, subfamily V, member 6
IDBP-810849
transient receptor potential cation channel, subfamily V, member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the vanilloid family of transient receptor potential (TRP) calcium channel proteins. Proteins in this TRP family have an N-terminal ankyrin repeat domain, which is required for channel assembly and regulation. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:142871203-142885762
Strand Reverse strand
Band q34
Transcripts
ENST00000359396 ENSP00000352358
ENST00000436401 ENSP00000411100
ENST00000431833 ENSP00000415917
ENST00000463646 ENSP00000479084
ENST00000485138
ENST00000474388
ENST00000489123
ENST00000615386
ENST00000619250
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0017158 regulation of calcium ion-dependent exocytosis
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029868
View Gene Order
ENSBTAG00000024219
Not yet available
Pathways
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
REACT_169333
TRP channels pathway
KEGG
hsa04970
Salivary secretion pathway
INOH
PID NCI
cd8tcrpathway
TCR signaling in naïve CD8+ T cells
tcr_pathway
TCR signaling in naïve CD4+ T cells
ptp1bpathway
Signaling events mediated by PTP1B
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.302740 Hs.682920 Hs.737376
RefSeq NM_018646
HUGO
OMIM
CCDS CCDS5874
HPRD 05982
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca