Homo sapiens Gene: TRPV6
Summary
InnateDB Gene IDBG-45160.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRPV6
Gene Name transient receptor potential cation channel, subfamily V, member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165125
Encoded Proteins
transient receptor potential cation channel, subfamily V, member 6
transient receptor potential cation channel, subfamily V, member 6
transient receptor potential cation channel, subfamily V, member 6
transient receptor potential cation channel, subfamily V, member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the vanilloid family of transient receptor potential (TRP) calcium channel proteins. Proteins in this TRP family have an N-terminal ankyrin repeat domain, which is required for channel assembly and regulation. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:142871203-142885762
Strand Reverse strand
Band q34
Transcripts
ENST00000359396 ENSP00000352358
ENST00000436401 ENSP00000411100
ENST00000431833 ENSP00000415917
ENST00000463646 ENSP00000479084
ENST00000485138
ENST00000474388
ENST00000489123
ENST00000615386
ENST00000619250
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005262 calcium channel activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
GO:0006811 ion transport
GO:0006816 calcium ion transport
GO:0017158 regulation of calcium ion-dependent exocytosis
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Stimuli-sensing channels pathway
Ion channel transport pathway
TRP channels pathway
KEGG
Salivary secretion pathway
INOH
PID BIOCARTA
PID NCI
TCR signaling in na´ve CD8+ T cells
TCR signaling in na´ve CD4+ T cells
Signaling events mediated by PTP1B
Cross-References
SwissProt
TrEMBL C9J9W0 Q9NXZ3
UniProt Splice Variant
Entrez Gene 55503
UniGene
RefSeq NM_018646
HUGO HGNC:14006
OMIM 606680
CCDS CCDS5874
HPRD
IMGT
EMBL AC104597 AJ277909
GenPept CAB92352
RNA Seq Atlas 55503