Homo sapiens Gene: MRPS26
Summary
InnateDB Gene IDBG-45275.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPS26
Gene Name mitochondrial ribosomal protein S26
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000125901
Encoded Proteins
mitochondrial ribosomal protein S26
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. This gene lies adjacent to and downstream of the gonadotropin-releasing hormone precursor gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:3045945-3048254
Strand Forward strand
Band p13
Transcripts
ENST00000380325 ENSP00000369682
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
Experimentally validated
Total 40 [view]
Protein-Protein 40 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0044822 poly(A) RNA binding
Biological Process
GO:0042769 DNA damage response, detection of DNA damage
GO:0043043 peptide biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9BYN8
TrEMBL
UniProt Splice Variant
Entrez Gene 64949
UniGene
RefSeq NM_030811
HUGO HGNC:14045
OMIM 611988
CCDS CCDS13043
HPRD
IMGT
EMBL AB051354 AL121905 BC013018
GenPept AAH13018 BAB54943 CAC10339
RNA Seq Atlas 64949