Version 5.4
Homo sapiens Gene: EAPP
Summary
InnateDB Gene IDBG-4543.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EAPP
Gene Name E2F-associated phosphoprotein
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000129518
Encoded Proteins
IDBP-4545
E2F-associated phosphoprotein
IDBP-601206
E2F-associated phosphoprotein
IDBP-590744
E2F-associated phosphoprotein
IDBP-812725
E2F-associated phosphoprotein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:34515929-34539711
Strand Reverse strand
Band q13.1
Transcripts
ENST00000250454 ENSP00000250454
ENST00000554792 ENSP00000450908
ENST00000555705 ENSP00000452439
ENST00000555683
ENST00000618169 ENSP00000483122
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0008284 positive regulation of cell proliferation
GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000054302
View Gene Order
ENSBTAG00000003419
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.433269 Hs.617453
RefSeq NM_018453
HUGO
OMIM
CCDS CCDS41941
HPRD 12631
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca