Version 5.4
Homo sapiens Gene: FOXL1
Summary
InnateDB Gene IDBG-45525.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FOXL1
Gene Name forkhead box L1
Synonyms FKH6; FKHL11; FREAC7;
Species Homo sapiens
Ensembl Gene ENSG00000176678
Encoded Proteins
IDBP-45527
forkhead box L1
IDBP-754656
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:86576368-86582160
Strand Forward strand
Band q24.1
Transcripts
ENST00000320241 ENSP00000326272
ENST00000593625 ENSP00000472376
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008301 DNA binding, bending
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0007495 visceral mesoderm-endoderm interaction involved in midgut development
GO:0007507 heart development
GO:0009887 organ morphogenesis
GO:0030111 regulation of Wnt signaling pathway
GO:0030166 proteoglycan biosynthetic process
GO:0061146 Peyer's patch morphogenesis
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q12952
TrEMBL M0R279
UniProt Splice Variant
Entrez Gene 2300
UniGene Hs.533830 Hs.626367
RefSeq NM_005250
HUGO HGNC:3817
OMIM 603252
CCDS CCDS10959
HPRD
IMGT
EMBL AC009108 AF315075 BC117226 U13225
GenPept AAA92042 AAG40312 AAI17227
RNA Seq Atlas 2300

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca