Homo sapiens Gene: FOXL1
Summary
InnateDB Gene IDBG-45525.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FOXL1
Gene Name forkhead box L1
Synonyms FKH6; FKHL11; FREAC7;
Species Homo sapiens
Ensembl Gene ENSG00000176678
Encoded Proteins
forkhead box L1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:86576368-86582160
Strand Forward strand
Band q24.1
Transcripts
ENST00000320241 ENSP00000326272
ENST00000593625 ENSP00000472376
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0008301 DNA binding, bending
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0007495 visceral mesoderm-endoderm interaction involved in midgut development
GO:0007507 heart development
GO:0009887 organ morphogenesis
GO:0030111 regulation of Wnt signaling pathway
GO:0030166 proteoglycan biosynthetic process
GO:0061146 Peyer's patch morphogenesis
Cellular Component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q12952
TrEMBL M0R279
UniProt Splice Variant
Entrez Gene 2300
UniGene Hs.533830 Hs.626367
RefSeq NM_005250
HUGO HGNC:3817
OMIM 603252
CCDS CCDS10959
HPRD
IMGT
EMBL AC009108 AF315075 BC117226 U13225
GenPept AAA92042 AAG40312 AAI17227
RNA Seq Atlas 2300