Homo sapiens Gene: GABRR3 | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-46636.6 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | GABRR3 | ||||||||||||||
Gene Name | gamma-aminobutyric acid receptor subunit rho-3 precursor | ||||||||||||||
Synonyms | |||||||||||||||
Species | Homo sapiens | ||||||||||||||
Ensembl Gene | ENSG00000183185 | ||||||||||||||
Encoded Proteins |
gamma-aminobutyric acid (GABA) receptor, rho 3
gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene)
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
The neurotransmitter gamma-aminobutyric acid (GABA) functions in the central nervous system to regulate synaptic transmission of neurons. This gene encodes one of three related subunits, which combine as homo- or hetero-pentamers to form GABA(C) receptors. In humans, some individuals contain a single-base polymorphism (dbSNP rs832032) that is predicted to inactivate the gene product. [provided by RefSeq, Jan 2012] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 3:97986673-98035304 | ||||||||||||||
Strand | Reverse strand | ||||||||||||||
Band | q11.2 | ||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
No orthologs found for this gene | |||||||||||||||
Pathways | |||||||||||||||
NETPATH | |||||||||||||||
REACTOME |
Ligand-gated ion channel transport pathway
GABA A (rho) receptor activation pathway
Transmembrane transport of small molecules pathway
Neuronal System pathway
GABA receptor activation pathway
Ion channel transport pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
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KEGG |
Neuroactive ligand-receptor interaction pathway
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INOH | |||||||||||||||
PID NCI | |||||||||||||||
Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | |||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | |||||||||||||||
UniGene | Hs.534578 | ||||||||||||||
RefSeq | NM_001105580 | ||||||||||||||
HUGO | |||||||||||||||
OMIM | |||||||||||||||
CCDS | CCDS54617 | ||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | |||||||||||||||
GenPept | |||||||||||||||
RNA Seq Atlas | |||||||||||||||