Version 5.4
Homo sapiens Gene: ZIC5
Summary
InnateDB Gene IDBG-46731.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZIC5
Gene Name Zic family member 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000139800
Encoded Proteins
IDBP-46733
Zic family member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 2, a related family member on chromosome 13. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:99962964-99971909
Strand Reverse strand
Band q32.3
Transcripts
ENST00000267294 ENSP00000267294
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0001843 neural tube closure
GO:0006355 regulation of transcription, DNA-templated
GO:0030154 cell differentiation
GO:0030900 forebrain development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041703
View Gene Order
ENSBTAG00000046271
Not yet available
Cross-References
SwissProt Q96T25
TrEMBL
UniProt Splice Variant
Entrez Gene 85416
UniGene Hs.508570
RefSeq NM_033132
HUGO HGNC:20322
OMIM
CCDS CCDS9494
HPRD
IMGT
EMBL AF378304 AL355338
GenPept AAK55418 CAH70366
RNA Seq Atlas 85416

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca