Version 5.4
Homo sapiens Gene: KRT12
Summary
InnateDB Gene IDBG-48295.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT12
Gene Name keratin 12
Synonyms K12
Species Homo sapiens
Ensembl Gene ENSG00000187242
Encoded Proteins
IDBP-48297
keratin 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:40861303-40867210
Strand Reverse strand
Band q21.2
Transcripts
ENST00000251643 ENSP00000251643
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
GO:0007601 visual perception
Cellular Component
GO:0005882 intermediate filament
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020912
View Gene Order
ENSBTAG00000015518
Not yet available
Cross-References
SwissProt Q99456
TrEMBL
UniProt Splice Variant
Entrez Gene 3859
UniGene Hs.66739
RefSeq NM_000223
HUGO HGNC:6414
OMIM 601687
CCDS CCDS11378
HPRD
IMGT
EMBL AB007119 AF137286 AK313747 CH471152 D78367
GenPept AAF61432 BAA11376 BAA25063 BAG36487 EAW60685
RNA Seq Atlas 3859

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca