Homo sapiens Gene: FGF14
Summary
InnateDB Gene IDBG-48304.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FGF14
Gene Name fibroblast growth factor 14
Synonyms FGF-14; FHF-4; FHF4; SCA27;
Species Homo sapiens
Ensembl Gene ENSG00000102466
Encoded Proteins
fibroblast growth factor 14
fibroblast growth factor 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:101710804-102402457
Strand Reverse strand
Band q33.1
Transcripts
ENST00000376143 ENSP00000365313
ENST00000376131 ENSP00000365301
ENST00000468052
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0008201 heparin binding
Biological Process
GO:0007165 signal transduction
GO:0007254 JNK cascade
GO:0007267 cell-cell signaling
GO:0007268 synaptic transmission
GO:0007399 nervous system development
GO:0008219 cell death
GO:0008344 adult locomotory behavior
GO:0010765 positive regulation of sodium ion transport
GO:0050905 neuromuscular process
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
KEGG
MAPK signaling pathway pathway
Regulation of actin cytoskeleton pathway
Pathways in cancer pathway
Melanoma pathway
INOH
GPCR signaling pathway
FGF signaling pathway pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.508616
RefSeq NM_004115 NM_175929
HUGO
OMIM
CCDS CCDS9500 CCDS9501
HPRD 03305
IMGT
EMBL
GenPept
RNA Seq Atlas