Homo sapiens Gene: OR4D6
Summary
InnateDB Gene IDBG-48309.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OR4D6
Gene Name olfactory receptor, family 4, subfamily D, member 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166884
Encoded Proteins
olfactory receptor, family 4, subfamily D, member 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:59456938-59457991
Strand Forward strand
Band q12.1
Transcripts
ENST00000300127 ENSP00000300127
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004984 olfactory receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0050911 detection of chemical stimulus involved in sensory perception of smell
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Olfactory Signaling Pathway pathway
KEGG
Olfactory transduction pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8NGJ1
TrEMBL
UniProt Splice Variant
Entrez Gene 219983
UniGene Hs.553650
RefSeq NM_001004708
HUGO HGNC:15175
OMIM
CCDS CCDS31562
HPRD
IMGT
EMBL AB065803 AF399569 BC137028 BC137029 BK004307 CH471076
GenPept AAI37029 AAI37030 AAK95054 BAC06022 DAA04705 EAW73845
RNA Seq Atlas 219983