Version 5.4
Mus musculus Gene: Rnf8
Summary
InnateDB Gene IDBG-486177.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnf8
Gene Name ring finger protein 8
Synonyms 3830404E21Rik; AIP37
Species Mus musculus
Ensembl Gene ENSMUSG00000090083
Encoded Proteins
IDBP-160895
ring finger protein 8
IDBP-533629
ring finger protein 8
IDBP-535411
ring finger protein 8
IDBP-625627
ring finger protein 8
IDBP-625628
ring finger protein 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:29614790-29641664
Strand Forward strand
Band A3.3
Transcripts
ENSMUST00000024817 ENSMUSP00000024817
ENSMUST00000162588 ENSMUSP00000124566
ENSMUST00000130871 ENSMUSP00000117838
ENSMUST00000161952
ENSMUST00000162417
ENSMUST00000161242
ENSMUST00000172485 ENSMUSP00000134697
ENSMUST00000173449 ENSMUSP00000133424
ENSMUST00000172800
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016881 acid-amino acid ligase activity
GO:0042393 histone binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006302 double-strand break repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0007067 mitotic nuclear division
GO:0007286 spermatid development
GO:0010212 response to ionizing radiation
GO:0016567 protein ubiquitination
GO:0033522 histone H2A ubiquitination
GO:0033523 histone H2B ubiquitination
GO:0043486 histone exchange
GO:0045190 isotype switching
GO:0045739 positive regulation of DNA repair
GO:0045900 negative regulation of translational elongation
GO:0051301 cell division
GO:0070534 protein K63-linked ubiquitination
GO:0070535 histone H2A K63-linked ubiquitination
GO:0070936 protein K48-linked ubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0030496 midbody
GO:0035861 site of double-strand break
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q8VC56
TrEMBL E0CY08 G3UWU4 G3UZZ4
UniProt Splice Variant
Entrez Gene 58230
UniGene Mm.305994
RefSeq NM_021419
OMIM
CCDS CCDS37538
HPRD
IMGT
MGI ID MGI:1929069
MGI Symbol Rnf8
EMBL AC154279 AC163629 AJ242721 AK076180 AK147168 BC021778 CT010295
GenPept AAH21778 BAC36236 BAE27732 CAB92239 CAJ18503
RNA Seq Atlas 58230

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca