Version 5.4
Homo sapiens Gene: IFT57
Summary
InnateDB Gene IDBG-48840.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFT57
Gene Name intraflagellar transport 57 homolog (Chlamydomonas)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000114446
Encoded Proteins
IDBP-48842
intraflagellar transport 57 homolog (Chlamydomonas)
IDBP-482183
intraflagellar transport 57 homolog (Chlamydomonas)
IDBP-478784
intraflagellar transport 57 homolog (Chlamydomonas)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:108160812-108222570
Strand Reverse strand
Band q13.13
Transcripts
ENST00000264538 ENSP00000264538
ENST00000468021
ENST00000478157 ENSP00000417768
ENST00000465024
ENST00000485979
ENST00000492106 ENSP00000417439
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 6 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0001843 neural tube closure
GO:0001947 heart looping
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007224 smoothened signaling pathway
GO:0016192 vesicle-mediated transport
GO:0042981 regulation of apoptotic process
GO:0050680 negative regulation of epithelial cell proliferation
GO:0060271 cilium morphogenesis
GO:0060972 left/right pattern formation
Cellular Component
GO:0005794 Golgi apparatus
GO:0005813 centrosome
GO:0005929 cilium
GO:0016020 membrane
GO:0030992 intraciliary transport particle B
GO:0032391 photoreceptor connecting cilium
GO:0036064 ciliary basal body
GO:0044292 dendrite terminus
GO:0072372 primary cilium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032965
View Gene Order
ENSBTAG00000005787
Not yet available
Pathways
NETPATH
REACTOME
REACT_228134
Signaling by Hedgehog pathway
REACT_111102
Signal Transduction pathway
REACT_267634
Hedgehog 'off' state pathway
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.412196 Hs.603921 Hs.605919
RefSeq NM_018010
HUGO
OMIM
CCDS CCDS2951
HPRD 09430
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca