Homo sapiens Gene: ASB10
Summary
InnateDB Gene IDBG-49302.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ASB10
Gene Name ankyrin repeat and SOCS box containing 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146926
Encoded Proteins
ankyrin repeat and SOCS box containing 10
ankyrin repeat and SOCS box containing 10
ankyrin repeat and SOCS box containing 10
ankyrin repeat and SOCS box containing 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:151175698-151187832
Strand Reverse strand
Band q36.1
Transcripts
ENST00000377867 ENSP00000367098
ENST00000275838 ENSP00000275838
ENST00000420175 ENSP00000391137
ENST00000415615 ENSP00000410871
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Antigen processing: Ubiquitination & Proteasome degradation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.647081
RefSeq NM_001142459 NM_001142460 NM_080871
HUGO
OMIM
CCDS CCDS47749 CCDS47750 CCDS5921
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas