Version 5.4
Homo sapiens Gene: ABCF2
Summary
InnateDB Gene IDBG-49350.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABCF2
Gene Name ATP-binding cassette, sub-family F (GCN20), member 2
Synonyms ABC28; EST133090; HUSSY18
Species Homo sapiens
Ensembl Gene ENSG00000033050
Encoded Proteins
IDBP-49352
ATP-binding cassette, sub-family F (GCN20), member 2
IDBP-49354
ATP-binding cassette, sub-family F (GCN20), member 2
IDBP-387398
ATP-binding cassette, sub-family F (GCN20), member 2
IDBP-484669
ATP-binding cassette, sub-family F (GCN20), member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the GCN20 subfamily. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding casette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 7. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:151207837-151227230
Strand Reverse strand
Band q36.1
Transcripts
ENST00000222388 ENSP00000222388
ENST00000287844 ENSP00000287844
ENST00000441774 ENSP00000395785
ENST00000473874
ENST00000468073 ENSP00000419720
ENST00000477252
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005524 ATP binding
GO:0016887 ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
Cellular Component
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0016020 membrane
GO:0043190 ATP-binding cassette (ABC) transporter complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028953
View Gene Order
ENSBTAG00000000607
Not yet available
Cross-References
SwissProt
TrEMBL C9JHK9
UniProt Splice Variant
Entrez Gene 10061
UniGene Hs.654958
RefSeq NM_005692 NM_007189 XM_005249931 XM_006715824
HUGO HGNC:71
OMIM 612510
CCDS CCDS5922 CCDS5923
HPRD 12403
IMGT
EMBL AC021097
GenPept
RNA Seq Atlas 10061

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca