Homo sapiens Gene: PCDHB1
InnateDB Gene IDBG-49838.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCDHB1
Gene Name protocadherin beta 1
Species Homo sapiens
Ensembl Gene ENSG00000171815
Encoded Proteins
protocadherin beta 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:141051135-141059344
Strand Forward strand
Band q31.3
ENST00000306549 ENSP00000307234
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
SwissProt Q9Y5F3
UniProt Splice Variant
Entrez Gene 29930
UniGene Hs.278950
RefSeq NM_013340
OMIM 606327
HPRD 08397
EMBL AF152488 BC112096 BC112098 CH471062
GenPept AAD43749 AAI12097 AAI12099 EAW61985
RNA Seq Atlas 29930