Version 5.4
Homo sapiens Gene: MIPOL1
Summary
InnateDB Gene IDBG-5073.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MIPOL1
Gene Name mirror-image polydactyly 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000151338
Encoded Proteins
IDBP-5075
mirror-image polydactyly 1
IDBP-237819
mirror-image polydactyly 1
IDBP-594249
mirror-image polydactyly 1
IDBP-602946
mirror-image polydactyly 1
IDBP-595708
mirror-image polydactyly 1
IDBP-602572
mirror-image polydactyly 1
IDBP-588135
mirror-image polydactyly 1
IDBP-588285
mirror-image polydactyly 1
IDBP-597791
mirror-image polydactyly 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:37197913-37552361
Strand Forward strand
Band q13.3
Transcripts
ENST00000327441 ENSP00000333539
ENST00000396294 ENSP00000379589
ENST00000556615 ENSP00000451297
ENST00000554930
ENST00000539062 ENSP00000438319
ENST00000556451 ENSP00000450479
ENST00000555870 ENSP00000452478
ENST00000556753 ENSP00000450575
ENST00000554114
ENST00000539174
ENST00000553349
ENST00000556940
ENST00000537471 ENSP00000444254
ENST00000545536 ENSP00000442529
ENST00000624539
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000047022
View Gene Order
ENSBTAG00000000655
Not yet available
Cross-References
SwissProt
TrEMBL G3V3K8
UniProt Splice Variant
Entrez Gene 145282
UniGene Hs.660396 Hs.684387
RefSeq NM_001195296 NM_001195297 NM_138731 XM_006720045
HUGO HGNC:21460
OMIM 606850
CCDS CCDS9664
HPRD 06029
IMGT
EMBL AL079304 AL109759 AL121790 AL121857
GenPept
RNA Seq Atlas 145282

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca