Homo sapiens Gene: CLC | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-50749.6 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | CLC | ||||||||||
Gene Name | Charcot-Leyden crystal protein | ||||||||||
Synonyms | Gal-10; GAL10; LGALS10; LGALS10A; LPPL_HUMAN | ||||||||||
Species | Homo sapiens | ||||||||||
Ensembl Gene | ENSG00000105205 | ||||||||||
Encoded Proteins |
Charcot-Leyden crystal protein
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 19:39731250-39738028 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | q13.2 | ||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
No orthologs found for this gene | |||||||||||
Cross-References | |||||||||||
SwissProt | Q05315 | ||||||||||
TrEMBL | |||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 1178 | ||||||||||
UniGene | |||||||||||
RefSeq | NM_001828 | ||||||||||
HUGO | HGNC:2014 | ||||||||||
OMIM | 153310 | ||||||||||
CCDS | CCDS33025 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AC005393 AC006133 BC119711 BC119712 CH471126 FJ613334 FJ613335 L01664 L01665 U68393 U68395 U68396 U68398 | ||||||||||
GenPept | AAA36190 AAC28912 AAC37530 AAC51157 AAI19712 AAI19713 ACR09636 ACR09637 EAW56914 | ||||||||||
RNA Seq Atlas | 1178 | ||||||||||