Version 5.4
Homo sapiens Gene: CARS2
Summary
InnateDB Gene IDBG-50790.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CARS2
Gene Name cysteinyl-tRNA synthetase 2, mitochondrial (putative)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134905
Encoded Proteins
IDBP-50792
cysteinyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-602448
cysteinyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-597108
cysteinyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-598709
cysteinyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-595378
cysteinyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-592982
cysteinyl-tRNA synthetase 2, mitochondrial (putative)
IDBP-809517
cysteinyl-tRNA synthetase 2, mitochondrial (putative)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 13:110641412-110713603
Strand Reverse strand
Band q34
Transcripts
ENST00000257347 ENSP00000257347
ENST00000375781
ENST00000481787
ENST00000471986
ENST00000487253 ENSP00000438267
ENST00000480437
ENST00000465145
ENST00000485188
ENST00000541239
ENST00000540006
ENST00000535516
ENST00000537802
ENST00000542774
ENST00000535615
ENST00000535398
ENST00000540215
ENST00000543487
ENST00000541362
ENST00000537386
ENST00000545506
ENST00000537404
ENST00000539405
ENST00000537743 ENSP00000443027
ENST00000539269 ENSP00000440420
ENST00000544488
ENST00000541443
ENST00000542126
ENST00000542709 ENSP00000444655
ENST00000537394 ENSP00000437962
ENST00000540629
ENST00000540785
ENST00000537412
ENST00000620794 ENSP00000480523
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004817 cysteine-tRNA ligase activity
GO:0004824 lysine-tRNA ligase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006423 cysteinyl-tRNA aminoacylation
GO:0006430 lysyl-tRNA aminoacylation
GO:0010467 gene expression
Cellular Component
GO:0005737 cytoplasm
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056228
View Gene Order
ENSBTAG00000011471
Not yet available
Pathways
NETPATH
REACTOME
REACT_15302
Mitochondrial tRNA aminoacylation pathway
REACT_15482
tRNA Aminoacylation pathway
REACT_71
Gene Expression pathway
KEGG
hsa00970
Aminoacyl-tRNA biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_024537
HUGO
OMIM
CCDS CCDS9514
HPRD 07763
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca