Homo sapiens Gene: SERTAD3
Summary
InnateDB Gene IDBG-51544.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERTAD3
Gene Name SERTA domain containing 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000167565
Encoded Proteins
SERTA domain containing 3
SERTA domain containing 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene was identified in a yeast two-hybrid assay employing the second subunit of human replication protein A as bait. It is localized to the nucleus and its expression is significantly higher in cancer cell lines compared to normal cell lines. This protein has also been shown to be a strong transcriptional co-activator. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:40440844-40444705
Strand Reverse strand
Band q13.2
Transcripts
ENST00000322354 ENSP00000325414
ENST00000392028 ENSP00000375882
ENST00000601217
ENST00000596456 ENSP00000472999
ENST00000599706 ENSP00000469245
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0030308 negative regulation of cell growth
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.515412
RefSeq NM_013368 NM_203344 XM_005258832
HUGO
OMIM
CCDS CCDS12558
HPRD 15327
IMGT
EMBL
GenPept
RNA Seq Atlas