Version 5.4
Homo sapiens Gene: CLEC14A
Summary
InnateDB Gene IDBG-5187.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLEC14A
Gene Name C-type lectin domain family 14, member A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176435
Encoded Proteins
IDBP-5189
C-type lectin domain family 14, member A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:38254103-38256369
Strand Reverse strand
Band q21.1
Transcripts
ENST00000342213 ENSP00000353013
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
Cellular Component
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045930
View Gene Order
ENSBTAG00000006130
Not yet available
Cross-References
SwissProt Q86T13
TrEMBL
UniProt Splice Variant
Entrez Gene 161198
UniGene Hs.525307
RefSeq NM_175060
HUGO HGNC:19832
OMIM
CCDS CCDS9667
HPRD
IMGT
EMBL AL161751 AY358395 AY573061 AY606132 BC031567 BX248017
GenPept AAH31567 AAQ88761 AAS77882 AAT92280 CAD62342
RNA Seq Atlas 161198

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca