Version 5.4
Homo sapiens Gene: HAUS6
Summary
InnateDB Gene IDBG-52373.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAUS6
Gene Name HAUS augmin-like complex, subunit 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147874
Encoded Proteins
IDBP-52375
HAUS augmin-like complex, subunit 6
IDBP-52377
HAUS augmin-like complex, subunit 6
IDBP-364654
HAUS augmin-like complex, subunit 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. This protein may have a role in efficient chromosome congression and segregation by promoting microtubule-dependent microtubule amplification. Pseudogenes of this gene are located on chromosomes 7 and 20. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:19053143-19103119
Strand Reverse strand
Band p22.1
Transcripts
ENST00000380502 ENSP00000369871
ENST00000380496 ENSP00000369865
ENST00000415524 ENSP00000409615
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
Experimentally validated
Total 32 [view]
Protein-Protein 32 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0007067 mitotic nuclear division
GO:0051225 spindle assembly
GO:0051297 centrosome organization
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005819 spindle
GO:0005874 microtubule
GO:0070652 HAUS complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038047
View Gene Order
ENSBTAG00000019843
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.533468 Hs.547758 Hs.594314 Hs.682466
RefSeq NM_001270890 NM_017645
HUGO
OMIM
CCDS CCDS6489
HPRD 13302
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca