Homo sapiens Gene: PDIA5
Summary
InnateDB Gene IDBG-52866.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDIA5
Gene Name protein disulfide isomerase family A, member 5
Synonyms PDIR;
Species Homo sapiens
Ensembl Gene ENSG00000065485
Encoded Proteins
protein disulfide isomerase family A, member 5
protein disulfide isomerase family A, member 5
protein disulfide isomerase family A, member 5
protein disulfide isomerase family A, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:123067062-123225227
Strand Forward strand
Band q21.1
Transcripts
ENST00000316218 ENSP00000323313
ENST00000489923 ENSP00000417520
ENST00000484644 ENSP00000419946
ENST00000495004
ENST00000472319
ENST00000467157
ENST00000485208
ENST00000469649 ENSP00000417199
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003756 protein disulfide isomerase activity
GO:0016209 antioxidant activity
GO:0016491 oxidoreductase activity
GO:0016853 isomerase activity
Biological Process
GO:0006457 protein folding
GO:0006987 activation of signaling protein activity involved in unfolded protein response
GO:0008152 metabolic process
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0034976 response to endoplasmic reticulum stress
GO:0044267 cellular protein metabolic process
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
IRE1alpha activates chaperones pathway
Unfolded Protein Response (UPR) pathway
XBP1(S) activates chaperone genes pathway
Metabolism of proteins pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.477352
RefSeq NM_006810
HUGO
OMIM
CCDS CCDS3020
HPRD 08334
IMGT
EMBL
GenPept
RNA Seq Atlas