Homo sapiens Gene: IL17B
Summary
InnateDB Gene IDBG-52942.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL17B
Gene Name interleukin 17B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000127743
Encoded Proteins
interleukin 17B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:149371324-149404202
Strand Reverse strand
Band q32
Transcripts
ENST00000261796 ENSP00000261796
ENST00000518814
ENST00000505432
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
Biological Process
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007267 cell-cell signaling
GO:1900017 positive regulation of cytokine production involved in inflammatory response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Cytokine-cytokine receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt Q9UHF5
TrEMBL
UniProt Splice Variant
Entrez Gene 27190
UniGene Hs.156979 Hs.409558
RefSeq NM_014443 XM_006714779
HUGO HGNC:5982
OMIM 604627
CCDS CCDS4297
HPRD 05217
IMGT
EMBL AF110385 AF152098 AF184969 AF212311 AF218727 AF386077 AY358931 BC113925 BC113946
GenPept AAF01318 AAF28104 AAF78775 AAG39637 AAG44136 AAI13926 AAI13947 AAK60336 AAQ89290
RNA Seq Atlas 27190