Version 5.4
Homo sapiens Gene: CEACAM3
Summary
InnateDB Gene IDBG-53253.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CEACAM3
Gene Name carcinoembryonic antigen-related cell adhesion molecule 3
Synonyms CD66D; CEA; CGM1; W264; W282
Species Homo sapiens
Ensembl Gene ENSG00000170956
Encoded Proteins
IDBP-53255
carcinoembryonic antigen-related cell adhesion molecule 3
IDBP-53259
carcinoembryonic antigen-related cell adhesion molecule 3
IDBP-380796
carcinoembryonic antigen-related cell adhesion molecule 3
IDBP-765434
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:41796437-41811553
Strand Forward strand
Band q13.2
Transcripts
ENST00000357396 ENSP00000349971
ENST00000344550 ENSP00000341725
ENST00000415495 ENSP00000411641
ENST00000599305
ENST00000595255
ENST00000599662
ENST00000596544 ENSP00000469333
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.11
RefSeq NM_001277163 NM_001815
HUGO
OMIM
CCDS CCDS12586 CCDS62685
HPRD 16450
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca