Homo sapiens Gene: NUP37
Summary
InnateDB Gene IDBG-53528.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUP37
Gene Name nucleoporin 37kDa
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000075188
Encoded Proteins
nucleoporin 37kDa
nucleoporin 37kDa
nucleoporin 37kDa
nucleoporin 37kDa
nucleoporin 37kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP37 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:102073103-102120124
Strand Reverse strand
Band q23.2
Transcripts
ENST00000251074 ENSP00000251074
ENST00000546385
ENST00000552283 ENSP00000448054
ENST00000547269 ENSP00000447284
ENST00000551744 ENSP00000448086
ENST00000551200
ENST00000543021
ENST00000548994
ENST00000550459 ENSP00000449982
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0005975 carbohydrate metabolic process
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0007077 mitotic nuclear envelope disassembly
GO:0008645 hexose transport
GO:0010827 regulation of glucose transport
GO:0015031 protein transport
GO:0015758 glucose transport
GO:0016032 viral process
GO:0019221 cytokine-mediated signaling pathway
GO:0044281 small molecule metabolic process
GO:0051028 mRNA transport
GO:0055085 transmembrane transport
Cellular Component
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005829 cytosol
GO:0031080 nuclear pore outer ring
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Transmembrane transport of small molecules pathway
Influenza Infection pathway
Interactions of Vpr with host cellular proteins pathway
Vpr-mediated nuclear import of PICs pathway
Myoclonic epilepsy of Lafora pathway
Antiviral mechanism by IFN-stimulated genes pathway
Glucose transport pathway
Hexose transport pathway
Cytokine Signaling in Immune system pathway
Metabolism of carbohydrates pathway
Late Phase of HIV Life Cycle pathway
Viral Messenger RNA Synthesis pathway
Transcriptional regulation by small RNAs pathway
Nuclear Pore Complex (NPC) Disassembly pathway
Influenza Viral RNA Transcription and Replication pathway
Interferon Signaling pathway
Separation of Sister Chromatids pathway
Mitotic Prometaphase pathway
Cell Cycle pathway
Immune System pathway
Regulation of Glucokinase by Glucokinase Regulatory Protein pathway
M Phase pathway
HIV Life Cycle pathway
Mitotic Anaphase pathway
Mitotic Prophase pathway
Rev-mediated nuclear export of HIV RNA pathway
Cell Cycle, Mitotic pathway
HIV Infection pathway
ISG15 antiviral mechanism pathway
Influenza Life Cycle pathway
Nuclear import of Rev protein pathway
Metabolism pathway
Host Interactions of HIV factors pathway
Resolution of Sister Chromatid Cohesion pathway
SLC-mediated transmembrane transport pathway
Interactions of Rev with host cellular proteins pathway
Gene Expression pathway
Nuclear Envelope Breakdown pathway
Disease pathway
Glycogen storage diseases pathway
Mitotic Metaphase and Anaphase pathway
Regulatory RNA pathways pathway
KEGG
RNA transport pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL F8VXF5
UniProt Splice Variant
Entrez Gene 79023
UniGene
RefSeq NM_024057 XM_005269144
HUGO HGNC:29929
OMIM 609264
CCDS CCDS9089
HPRD 14853
IMGT
EMBL AC079907
GenPept
RNA Seq Atlas 79023