Homo sapiens Gene: IFNA16
Summary
InnateDB Gene IDBG-53891.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IFNA16
Gene Name interferon, alpha 16
Synonyms IFN-alphaO;
Species Homo sapiens
Ensembl Gene ENSG00000147885
Encoded Proteins
interferon, alpha 16
interferon, alpha 16
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:21216373-21239935
Strand Reverse strand
Band p21.3
Transcripts
ENST00000380216 ENSP00000369564
ENST00000616765 ENSP00000483323
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005126 cytokine receptor binding
GO:0005132 type I interferon receptor binding
Biological Process
GO:0002250 adaptive immune response
GO:0002286 T cell activation involved in immune response
GO:0002323 natural killer cell activation involved in immune response
GO:0006952 defense response
GO:0006959 humoral immune response
GO:0007596 blood coagulation
GO:0019221 cytokine-mediated signaling pathway
GO:0030183 B cell differentiation
GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein
GO:0042100 B cell proliferation
GO:0043330 response to exogenous dsRNA
GO:0045087 innate immune response
GO:0045343 regulation of MHC class I biosynthetic process
GO:0051607 defense response to virus
GO:0060337 type I interferon signaling pathway
GO:0060338 regulation of type I interferon-mediated signaling pathway
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Interferon alpha/beta signaling pathway
Cytokine Signaling in Immune system pathway
Innate Immune System pathway
TRAF6 mediated IRF7 activation pathway
Regulation of IFNA signaling pathway
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways pathway
Interferon Signaling pathway
Immune System pathway
Factors involved in megakaryocyte development and platelet production pathway
Hemostasis pathway
KEGG
Cytokine-cytokine receptor interaction pathway
Regulation of autophagy pathway
Toll-like receptor signaling pathway pathway
RIG-I-like receptor signaling pathway pathway
Cytosolic DNA-sensing pathway pathway
Jak-STAT signaling pathway pathway
Natural killer cell mediated cytotoxicity pathway
Hepatitis C pathway
Autoimmune thyroid disease pathway
INOH
GPCR signaling pathway
IFN alpha signaling pathway
JAK STAT pathway and regulation pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt P05015
TrEMBL Q9UMJ2
UniProt Splice Variant
Entrez Gene 3449
UniGene Hs.56303 Hs.93907
RefSeq NM_002173
HUGO HGNC:5421
OMIM 147580
CCDS CCDS34996
HPRD
IMGT
EMBL AL512606 CH471071 K02055 M10201 M28585 X02957
GenPept AAA36042 AAA52727 AAA52732 CAA26703 CAH71193 EAW58618
RNA Seq Atlas 3449