Homo sapiens Gene: PSG6
Summary
InnateDB Gene IDBG-54785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PSG6
Gene Name pregnancy specific beta-1-glycoprotein 6
Synonyms PSBG-10; PSBG-12; PSBG-6; PSG10; PSGGB;
Species Homo sapiens
Ensembl Gene ENSG00000170848
Encoded Proteins
pregnancy specific beta-1-glycoprotein 6
pregnancy specific beta-1-glycoprotein 6
pregnancy specific beta-1-glycoprotein 6
pregnancy specific beta-1-glycoprotein 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The protein encoded by this gene contains the Arg-Gly-Asp tripeptide associated with cellular adhesion and recognition. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:42728080-43205603
Strand Reverse strand
Band q13.31
Transcripts
ENST00000187910 ENSP00000187910
ENST00000292125 ENSP00000292125
ENST00000402603 ENSP00000385736
ENST00000402456
ENST00000484292
ENST00000599753 ENSP00000472935
ENST00000601833 ENSP00000469423
ENST00000594375 ENSP00000470412
ENST00000595062
ENST00000621241 ENSP00000482453
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007565 female pregnancy
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q00889
TrEMBL B5MCE1 M0QXW0 M0QZA7
UniProt Splice Variant
Entrez Gene 5675
UniGene Hs.596258 Hs.646353 Hs.680533
RefSeq NM_001031850 NM_002782
HUGO HGNC:9523
OMIM 176395 176399
CCDS CCDS12613 CCDS33038
HPRD
IMGT
EMBL AC005260 AH002953 AH007627 BC020652 M31125 M32620 M32621 M33666 X17098
GenPept AAA36512 AAA60201 AAA60202 AAA60206 AAC25619 AAC25620 AAD28501 AAH20652 CAA34957
RNA Seq Atlas 5675