Version 5.4
Homo sapiens Gene: ABTB1
Summary
InnateDB Gene IDBG-54981.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABTB1
Gene Name ankyrin repeat and BTB (POZ) domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000114626
Encoded Proteins
IDBP-54983
ankyrin repeat and BTB (POZ) domain containing 1
IDBP-383571
ankyrin repeat and BTB (POZ) domain containing 1
IDBP-477766
ankyrin repeat and BTB (POZ) domain containing 1
IDBP-482643
ankyrin repeat and BTB (POZ) domain containing 1
IDBP-479867
ankyrin repeat and BTB (POZ) domain containing 1
IDBP-482414
ankyrin repeat and BTB (POZ) domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:127672935-127680920
Strand Forward strand
Band q21.3
Transcripts
ENST00000232744 ENSP00000232744
ENST00000453791 ENSP00000412684
ENST00000483857 ENSP00000420748
ENST00000475265
ENST00000493365
ENST00000475042 ENSP00000418641
ENST00000466612
ENST00000479280
ENST00000467179
ENST00000468137 ENSP00000417366
ENST00000464431
ENST00000491633
ENST00000478298
ENST00000474129
ENST00000497162 ENSP00000418439
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003746 translation elongation factor activity
GO:0005515 protein binding
Biological Process
GO:0006414 translational elongation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030083
View Gene Order
ENSBTAG00000018238
Not yet available
Cross-References
SwissProt
TrEMBL F2Z3F5
UniProt Splice Variant
Entrez Gene 80325
UniGene Hs.107812
RefSeq NM_032548 NM_172027 XM_006713768 XM_006713769 XM_006713771 XM_006713772
HUGO HGNC:18275
OMIM 608308
CCDS CCDS3045 CCDS46901
HPRD 10513
IMGT
EMBL AC023593
GenPept
RNA Seq Atlas 80325

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca