Homo sapiens Gene: SNRNP27
Summary
InnateDB Gene IDBG-55069.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNRNP27
Gene Name small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000124380
Encoded Proteins
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a serine/arginine-rich (SR) protein. SR proteins play important roles in pre-mRNA splicing by facilitating the recognition and selection of splice sites. The encoded protein associates with the 25S U4/U6.U5 tri-snRNP, a major component of the U2-type spiceosome. The expression of this gene may be altered in cells infected with the human T-cell lymphotropic virus type 1 (HTLV-1) retrovirus. A pseudogene of this gene is located on the long arm of chromosome 5. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:69893560-69905575
Strand Forward strand
Band p13.3
Transcripts
ENST00000244227 ENSP00000244227
ENST00000409116 ENSP00000386608
ENST00000450162 ENSP00000395144
ENST00000488986
ENST00000487029 ENSP00000430449
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0008150 biological_process
GO:0008380 RNA splicing
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 11017
UniGene Hs.54649 Hs.712944
RefSeq NM_006857
HUGO HGNC:30240
OMIM
CCDS CCDS33219
HPRD 15288
IMGT
EMBL
GenPept
RNA Seq Atlas 11017