Version 5.4
Homo sapiens Gene: ACAD9
Summary
InnateDB Gene IDBG-55357.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACAD9
Gene Name acyl-CoA dehydrogenase family, member 9
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000177646
Encoded Proteins
IDBP-55359
acyl-CoA dehydrogenase family, member 9
IDBP-474737
acyl-CoA dehydrogenase family, member 9
IDBP-482528
acyl-CoA dehydrogenase family, member 9
IDBP-474640
acyl-CoA dehydrogenase family, member 9
IDBP-484841
acyl-CoA dehydrogenase family, member 9
IDBP-475314
acyl-CoA dehydrogenase family, member 9
IDBP-479940
acyl-CoA dehydrogenase family, member 9
IDBP-477395
acyl-CoA dehydrogenase family, member 9
IDBP-484543
acyl-CoA dehydrogenase family, member 9
IDBP-810219
acyl-CoA dehydrogenase family, member 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the acyl-CoA dehydrogenase family. Members of this family of proteins localize to the mitochondria and catalyze the rate-limiting step in the beta-oxidation of fatty acyl-CoA. The encoded protein is specifically active toward palmitoyl-CoA and long-chain unsaturated substrates. Mutations in this gene cause acyl-CoA dehydrogenase family member type 9 deficiency. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:128879490-128916067
Strand Forward strand
Band q21.3
Transcripts
ENST00000308982 ENSP00000312618
ENST00000505602
ENST00000514643 ENSP00000422020
ENST00000512801 ENSP00000427283
ENST00000511227 ENSP00000425226
ENST00000505192 ENSP00000426277
ENST00000515429 ENSP00000426189
ENST00000514336 ENSP00000423758
ENST00000505867 ENSP00000425346
ENST00000511526
ENST00000508971 ENSP00000422683
ENST00000511325
ENST00000620948 ENSP00000478191
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 15 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003995 acyl-CoA dehydrogenase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0030425 dendrite
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027710
View Gene Order
ENSBTAG00000003242
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.567482
RefSeq NM_014049
HUGO
OMIM
CCDS CCDS3053
HPRD 12412
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca