Version 5.4
| Homo sapiens Gene: NDUFB6 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-56034.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | NDUFB6 | ||||||||||||||||||
| Gene Name | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | ||||||||||||||||||
| Synonyms | B17; CI | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000165264 | ||||||||||||||||||
| Encoded Proteins |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jan 2011] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 9:32552999-32573184 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | p21.1 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Respiratory electron transport pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
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| KEGG |
Alzheimer's disease pathway
Oxidative phosphorylation pathway
Parkinson's disease pathway
Huntington's disease pathway
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| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | O95139 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 4712 | ||||||||||||||||||
| UniGene | |||||||||||||||||||
| RefSeq | NM_001199987 NM_002493 NM_182739 | ||||||||||||||||||
| HUGO | HGNC:7701 | ||||||||||||||||||
| OMIM | 603322 | ||||||||||||||||||
| CCDS | CCDS6528 CCDS6529 CCDS75826 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AF035840 AF067167 AK289702 AL353671 BC009801 BC029247 BI669356 CH471071 CR456920 | ||||||||||||||||||
| GenPept | AAC68838 AAD32451 AAH09801 AAH29247 BAF82391 CAG33201 CAH71257 CAH71258 EAW58541 EAW58542 | ||||||||||||||||||
| RNA Seq Atlas | 4712 | ||||||||||||||||||