Homo sapiens Gene: OSBPL7
Summary
InnateDB Gene IDBG-56184.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSBPL7
Gene Name oxysterol binding protein-like 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000006025
Encoded Proteins
oxysterol binding protein-like 7
oxysterol binding protein-like 7
oxysterol binding protein-like 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:47807372-47821834
Strand Reverse strand
Band q21.32
Transcripts
ENST00000007414 ENSP00000007414
ENST00000392507 ENSP00000376295
ENST00000579728 ENSP00000463599
ENST00000584698
ENST00000580226
ENST00000578461 ENSP00000464624
ENST00000580140
ENST00000585051
ENST00000580808
ENST00000583167
ENST00000613735 ENSP00000479827
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0015485 cholesterol binding
Biological Process
GO:0006869 lipid transport
GO:0071397 cellular response to cholesterol
GO:1901800 positive regulation of proteasomal protein catabolic process
Cellular Component
GO:0005776 autophagic vacuole
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0097038 perinuclear endoplasmic reticulum
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_145798 XM_005257010
HUGO
OMIM
CCDS CCDS11515
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas