Version 5.4
Homo sapiens Gene: APOL4
Summary
InnateDB Gene IDBG-5672.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOL4
Gene Name apolipoprotein L, 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000100336
Encoded Proteins
IDBP-5674
apolipoprotein L, 4
IDBP-5676
apolipoprotein L, 4
IDBP-5678
apolipoprotein L, 4
IDBP-235716
apolipoprotein L, 4
IDBP-374498
apolipoprotein L, 4
IDBP-374500
apolipoprotein L, 4
IDBP-374506
apolipoprotein L, 4
IDBP-588036
apolipoprotein L, 4
IDBP-810851
apolipoprotein L, 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the apolipoprotein L family and may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Two transcript variants encoding two different isoforms have been found for this gene. Only one of the isoforms appears to be a secreted protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:36189124-36204840
Strand Reverse strand
Band q12.3
Transcripts
ENST00000332987 ENSP00000333229
ENST00000352371 ENSP00000338260
ENST00000328429 ENSP00000331089
ENST00000397275 ENSP00000380445
ENST00000457630 ENSP00000409085
ENST00000419360 ENSP00000395548
ENST00000449084
ENST00000436763 ENSP00000393096
ENST00000493203 ENSP00000432133
ENST00000480236
ENST00000613247
ENST00000616056 ENSP00000483497
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0008289 lipid binding
Biological Process
GO:0006629 lipid metabolic process
GO:0006869 lipid transport
GO:0042157 lipoprotein metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.115099
RefSeq NM_030643 NM_145660
HUGO
OMIM
CCDS CCDS74851 CCDS74852
HPRD 16237
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca